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A viral infection can cause type I diabetes mellitus.

A) True
B) False

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Any heightened or inappropriate immune response resulting in tissue damage is called a(n)


A) autoimmune disease.
B) immunodeficiency.
C) hypersensitivity.
D) transfusion reaction.
E) desensitization.

F) A) and D)
G) A) and C)

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C

Epinephrine


A) is an antihistamine.
B) reverses constriction of airways.
C) causes desensitization.
D) inhibits the activity of lymphocytes.
E) All of the choices are correct.

F) C) and D)
G) B) and E)

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Tissue transplanted from one body site on a patient to a different body site on that patient is called a(n)


A) isograft.
B) autograft.
C) allograft.
D) xenograft.
E) hypograft.

F) A) and D)
G) A) and C)

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A secondary acquired immunodeficiency is


A) AIDS.
B) adenosine deaminase (ADA) deficiency.
C) DiGeorge syndrome.
D) agammaglobulinemia.
E) SCID.

F) A) and C)
G) D) and E)

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The study of diseases associated with excesses and deficiencies of the immune system is


A) humoralpathology.
B) hemopathology.
C) epidemiology.
D) immunopathology.
E) histopathology.

F) A) and D)
G) None of the above

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Each of the following is an autoimmune disease except


A) systemic lupus erythematosus.
B) Graves' disease.
C) type I diabetes.
D) metastatic cancer.
E) rheumatic fever.

F) A) and B)
G) B) and D)

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An antihistamine will


A) inhibit the activity of lymphocytes.
B) bind to histamine receptors on target organs.
C) block synthesis of leukotrienes.
D) relieve inflammatory symptoms.
E) reverse spasms of respiratory smooth muscles.

F) C) and D)
G) A) and B)

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What can be a consequence of a genetic deficiency in B-cell survival and maturity?


A) host rejection of graft
B) graft versus host disease
C) formation of autoantibodies
D) hypogammaglobulinemia
E) None of the choices is correct.

F) A) and D)
G) None of the above

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Food allergies include gastrointestinal symptoms and often hives.

A) True
B) False

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Please read the clinical scenario, and then answer the question that follow to become familiar with the traditional NCLEX question format. Mark is a 9-year-old Hispanic boy who has come into your emergency room complaining of “chest tightness” and “difficulty breathing.” You notice that he is frequently coughing, and his lungs sound very wheezy. His chest X ray shows lungs that are overexpanded. His mom said that he had five episodes like this one over the past few years, but none this bad. Recently, he’s had 5 episodes over the previous month, each lasting about a day. -What is the most likely development and progression of Mark's asthma?


A) IgE-mediated response with lung tissue that is hypersensitive to products of mast cell degranulation
B) IgE response that causes the body to not recognize its own lung tissue,and fights against it by constricting bronchioles
C) IgG-mediated response with lung tissue that is hypersensitive to products of mast cell degranulation
D) IgG response that causes the body to not recognize its own lung tissue,and fights against it by constricting bronchioles

E) A) and C)
F) B) and C)

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A xenograft is graft tissue from a donor of one species transplanted to a recipient of another species.

A) True
B) False

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True

Please read the clinical scenario, and then answer the question that follow to become familiar with the traditional NCLEX question format. Marian is a 28-year-old woman who is 30 weeks' pregnant with her second child. Her first pregnancy and delivery was uncomplicated, and she now has a healthy 2-year-old girl. However, it is known that she is Rh-, and this child could be at risk for hemolytic disease of the newborn. She did receive RhoGAM with her first pregnancy. She presents to your maternal-fetal medicine clinic for a checkup, as she is a medium-risk pregnant mom. -After further investigation,it is learned that the father is Rh+,and so was the first child.However,Marian declines the RhoGAM injection because "there were no complications with my first pregnancy and delivery,how can you be sure there will be with this one?" Plus,she also explains how unpleasant the RhoGAM injection was with her first pregnancy,and she would like to avoid it,if at all possible.What is an appropriate response?


A) "I didn't realize you received RhoGAM with your first pregnancy.There's a good chance you don't need it this time after all."
B) "It is important you receive your RhoGAM injection,because this child will probably develop hemolytic disease of the newborn if you don't."
C) "It is important that we keep you from being sensitized to Rh factor,otherwise future pregnancies will be at risk for developing hemolytic disease of the newborn."
D) "You were probably sensitized to Rh factor with your first pregnancy,so the chances are decreased that this child will develop hemolytic disease of the newborn.I'll ask the doctor if we can forego the injection."

E) A) and D)
F) All of the above

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Which of the following is not a theory to explain the origin of autoimmune diseases?


A) sequestered antigen theory
B) clonal selection theory
C) theory of immune deficiency
D) viral infection theory
E) All of the choices are possible theories.

F) A) and E)
G) All of the above

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A person who are Rh- will have anti-Rh antibodies in their serum from early infancy.

A) True
B) False

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False

AIDS is a secondary immunodeficiency disease that affects several types of immune cells.

A) True
B) False

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The chemical mediator that causes prolonged bronchospasm,vascular permeability,and mucus secretion of asthmatic patients is


A) prostaglandin.
B) histamine.
C) leukotriene.
D) serotonin.
E) platelet-activating factor.

F) A) and B)
G) A) and C)

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Systemic anaphylaxis can quickly result in airway blockage,shock,and death.

A) True
B) False

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Please read the clinical scenario, and then answer the question that follow to become familiar with the traditional NCLEX question format. Mark is a 9-year-old Hispanic boy who has come into your emergency room complaining of “chest tightness” and “difficulty breathing.” You notice that he is frequently coughing, and his lungs sound very wheezy. His chest X ray shows lungs that are overexpanded. His mom said that he had five episodes like this one over the past few years, but none this bad. Recently, he’s had 5 episodes over the previous month, each lasting about a day. -What is the most likely diagnosis for Mark?


A) asthma
B) hay fever
C) seasonal allergy
D) drug allergy

E) All of the above
F) C) and D)

Correct Answer

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Allergic reactions to penicillins are considered a(n) _____ hypersensitivity.


A) T-cell mediated
B) antibody mediated
C) immune complex mediated
D) immediate
E) both T-cell mediated and antibody mediated

F) D) and E)
G) A) and D)

Correct Answer

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