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Which one of the following steps does not occur during multiplication of a Picornavirus?


A) Synthesis of viral proteins
B) Synthesis of - strands of RNA
C) Synthesis of + strands of RNA
D) Synthesis of DNA
E) None of the above

F) A) and B)
G) B) and C)

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A clear area against a confluent "lawn" of bacteria is called a


A) Plaque.
B) Phage.
C) Cell lysis.
D) Pock.
E) None of the above.

F) B) and E)
G) A) and C)

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Lysogeny can result in all of the following except


A) Transduction of specific genes.
B) Immunity to reinfection by the same phage.
C) Immunity to reinfection by any phage.
D) Acquisition of new characteristics by the host cell.
E) None of the above.

F) A) and E)
G) A) and B)

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Which of the following statements is not true?


A) Prophage genes are represented by a repressor protein coded for by the prophage.
B) A prophage is phage DNA inserted into a bacterial chromosome.
C) A prophage may result in new properties of the host cell.
D) The prophage makes the host cell immune to infection by other phages.
E) A prophage can pop out of the chromosome.

F) B) and E)
G) A) and B)

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A persistent infection is an infection in which


A) The disease process occurs gradually over a long period.
B) Host cells are transformed.
C) The virus remains in equilibrium with the host without causing a disease.
D) Host cells are gradually lysed.
E) Viral replication is unusually slow.

F) B) and C)
G) C) and D)

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Which of the following would be the first step in biosynthesis of a virus with a - strand of RNA?


A) Synthesis of double- stranded RNA from an RNA template
B) Transcription of mRNA from DNA
C) Synthesis of DNA from an RNA template
D) Synthesis of double- stranded RNA from a DNA template
E) None of the above

F) C) and D)
G) A) and C)

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An example of a latent viral infection is


A) Cold sores.
B) Subacute sclerosing panencephalitis.
C) Influenza.
D) Smallpox.
E) None of the above.

F) C) and D)
G) A) and D)

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Viruses that have reverse transcriptase are in the


A) Bacteriophage families.
B) Influenzavirus.
C) Retroviridae and Picornaviridae.
D) Herpesviridae and Retroviridae.
E) Hepadnaviridae and Retroviridae.

F) A) and B)
G) A) and C)

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The following steps occur during multiplication of Retroviruses. What is the fourth step?


A) Attachment
B) Penetration
C) Synthesis of + RNA
D) Uncoating
E) Synthesis of double- stranded DNA

F) B) and E)
G) None of the above

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Figure 13.1 Figure 13.1    -In Figure 13.1, the structures illustrated are composed of A)  RNA B)  DNA C)  Capsomeres D)  Capsids E)  DNA or RNA -In Figure 13.1, the structures illustrated are composed of


A) RNA
B) DNA
C) Capsomeres
D) Capsids
E) DNA or RNA

F) B) and D)
G) B) and C)

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In which of the following ways do viruses differ from bacteria?


A) Viruses are filterable.
B) Viruses are obligate intracellular parasites.
C) Viruses are not composed of cells.
D) Viruses don't have any nucleic acid.
E) All of the above.

F) C) and E)
G) A) and B)

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Some viruses, such as Human Herpes Virus 1, infect a cell without causing symptoms; these are called


A) Slow viruses.
B) Lytic viruses.
C) Phages.
D) Latent viruses.
E) Unconventional viruses.

F) A) and E)
G) C) and E)

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Continuous cell lines differ from primary cell lines in that


A) Continuous cell lines are derived from primary cell lines.
B) Viruses can be grown in continuous cell lines.
C) Continuous cell lines are from human embryos.
D) Continuous cell lines always have to be reisolated from animal tissues.
E) Continuous cell lines can be maintained through an indefinite number of generations.

F) None of the above
G) A) and E)

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Which of the following is not true about viruses?


A) Viruses contain DNA or RNA but never both.
B) Viruses use the anabolic machinery of the cell.
C) Viruses contain a protein coat.
D) Viruses use their own catabolic enzymes.
E) None of the above.

F) C) and E)
G) C) and D)

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A viroid is


A) A naked, infectious piece of RNA.
B) A complete, infectious virus particle.
C) A provirus.
D) A capsid without a nucleic acid.
E) None of the above.

F) A) and E)
G) C) and E)

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Approximately how many virus particles could fit along a 1 millimeter line?


A) 20,000
B) 2,000,000
C) 2
D) 20
E) 200

F) A) and B)
G) A) and E)

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Bacteriophages derive all of the following from the host cell except


A) tRNA.
B) Nucleotides.
C) Lysozyme.
D) Amino acids.
E) None of the above.

F) B) and C)
G) B) and D)

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Nontoxic strains of Vibrio cholerae can become toxic when they are in the human intestine with toxic strains of bacteria. This suggests that the toxin genes are acquired by


A) Prions.
B) Reverse transcriptase.
C) Host enzymes.
D) Transduction.
E) None of the above.

F) C) and E)
G) C) and D)

Correct Answer

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Generally, in a DNA- containing virus infection, the host animal cell supplies all of the following Except


A) RNA polymerase.
B) tRNA.
C) DNA polymerase.
D) Nucleotides.
E) None of the above.

F) A) and C)
G) B) and E)

Correct Answer

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Which one of the following steps does not occur during multiplication of a Rhabdovirus?


A) Synthesis of DNA
B) Synthesis of viral proteins
C) Synthesis of - strands of RNA
D) Synthesis of + strands of RNA

E) A) and B)
F) A) and C)

Correct Answer

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