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The DiGeorge syndrome is the result of


A) autoantibodies.
B) delayed hypersensitivity.
C) congenital absence or immaturity of the thymus gland.
D) failure of B cell development and maturity.
E) a genetic defect in the development of both T-cells and B cells.

F) B) and C)
G) A) and B)

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The potential for hemolytic disease of the newborn occurs when


A) maternal Rh+ cells enter an Rh− fetus.
B) fetal Rh+ cells enter an Rh− mother.
C) maternal Rh− cells enter an Rh+ fetus.
D) fetal Rh− cells enter an Rh+ mother.
E) fetal Rh+ cells enter an Rh+ mother.

F) A) and D)
G) A) and B)

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The practice of delaying the introduction of solid foods may help prevent the development of food allergies, but doesn't provide complete protection.

A) True
B) False

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Type _____ hypersensitivities involve soluble antigen with IgM or IgG forming complexes that can deposit in tissues.


A) 1
B) 2
C) 3
D) 4

E) A) and C)
F) A) and B)

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C

Treatment for agammaglobulinemia is


A) frequent transfusions of Rh+ blood.
B) passive immunotherapy and continuous antibiotic therapy.
C) bone marrow transplant.
D) allografts of skin.
E) continuous immunosuppressive therapy.

F) C) and D)
G) B) and D)

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B

Systemic anaphylaxis can quickly result in airway blockage, shock, and death.

A) True
B) False

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Atopy and anaphylaxis are hypersensitivities in the category


A) Type 1 only.
B) Type 1 and Type 4.
C) Type 4 only.
D) Type 1, Type 2, Type 3.
E) Type 1, Type 2, Type 3, and Type 4.

F) A) and D)
G) All of the above

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The antigens to which allergic individuals are sensitive are termed _____.

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Allergic patients receiving small, controlled injections of specific allergens are undergoing


A) desensitization.
B) sensitization.
C) tissue matching.
D) degranulation.

E) B) and D)
F) A) and B)

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Which of the following methods is/are used for determining the most appropriate donor tissue for a particular recipient?


A) tissue typing
B) mixed lymphocyte reaction
C) ABO blood typing
D) All of these choices are correct.

E) A) and C)
F) A) and B)

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Which of the following can be a consequence of a genetic deficiency in B cell survival and maturity?


A) host rejection of graft
B) graft versus host disease
C) formation of autoantibodies
D) hypogammaglobulinemia

E) A) and B)
F) None of the above

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D

Allergic reactions to penicillin are an example of a


A) Type 1 hypersensitivity.
B) Type 2 hypersensitivity.
C) Type 3 hypersensitivity.
D) Type 4 hypersensitivity.

E) A) and B)
F) A) and C)

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Histamine causes all the following, except


A) increased sensitivity to light.
B) constriction of smooth muscle of bronchi and the intestine.
C) relaxes vascular smooth muscle.
D) wheal and flare reaction in skin.
E) pruritis and headache.

F) All of the above
G) A) and E)

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Epinephrine


A) is an antihistamine.
B) reverses constriction of airways.
C) causes desensitization.
D) inhibits the activity of lymphocytes.
E) All of these choices are correct.

F) A) and C)
G) A) and E)

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The most common immunoglobulin deficiency is an IgG deficiency.

A) True
B) False

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Which of the following does not belong with transformed cancer cells?


A) oncogenic viruses
B) increased rate of growth
C) chromosomal alterations
D) capacity for limited division
E) changed surface molecules

F) A) and B)
G) A) and C)

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All of the following are associated with IgE_ and mast cell-mediated allergy, except


A) drug allergy.
B) eczema.
C) anaphylaxis.
D) allergic asthma.
E) systemic lupus erythematosus.

F) A) and B)
G) A) and C)

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Severe combined immunodeficiencies SCIDs) are due to


A) autoantibodies.
B) delayed hypersensitivity.
C) congenital absence or immaturity of the thymus gland.
D) failure of B cell development and maturity.
E) a genetic defect in the development of both T-cells and B cells.

F) All of the above
G) B) and E)

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Jose needs a kidney due to his diabetes. His sister is a close match and is willing to give him one of hers. What type of transplant is this?


A) allograft
B) xenograft
C) autograft
D) heterograft

E) B) and C)
F) All of the above

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Food allergies include gastrointestinal symptoms as well as skin and respiratory symptoms.

A) True
B) False

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